Quick Links: Skip to main page content Skip to Search Skip to Topics Menu Skip to Common Links
  • Decrease font size
  • Return font size to normal
  • Increase font size
U.S. Department of Health and Human Services

Final Rules: Food Additives and Color Additives
  • Print
  • Share
  • E-mail
-

Petition(s): GRP 8G0337

Direct Food Substances Affirmed as Generally Recognized as Safe; Chymosin Enzyme Preparation Derived From Escherichia Coli K-12

Petitioner: Pfizer Central Research (Pfizer)
Docket number (legacy and/or former docket number(s)): (87G-0418, 87F-0416)
Subject additive and intended use: amending its regulations to affirm that the use of chymosin preparation derived by fermentation from Escherichia coli K-12 is generally recognized as safe (GRAS)
21 CFR* affected: 184.1685 Rennet (animal-derived) and chymosin preparation (fermentation-derived)
Substance(s)*, (CAS Registry® No.): chymosin preparation, Escherichia coli K-12
Federal Register publication history: Feb 9, 1988 53 FR 3792 Notice
Mar 23, 1990 55 FR 10932 Final rule Mar 23, 1990

 

*Definitions

  • 21 CFR: Title 21 of the Code of Federal Regulations.
  • Substance: The name of the substance listed in the CFR.
  • CAS Registry® No.: Chemical Abstract Service (CAS) Registry Number® for the substance.
  • Petitions (see also Questions and Answers About the Petition Process)
    • FAP: Food Additive Petition
    • CAP: Color Additive Petition
    • GRP: GRAS Affirmation Petition (replaced by GRAS Notification Program in 1998)
-
-