Petition(s): GRP 9G0352

Direct Food Substances Affirmed as Generally Recognized as Safe; Chymosin Enzyme Preparation Derived From Aspergillus Niger Van Tieghem Variety Awamori (Nakazawa) Al-Musallam

• Petitioner: Genencor, Inc., now Genencor International, Inc.
• Docket number (legacy and/or former docket number(s)): (89G-0384)
• Subject additive and intended use: amending its regulations to affirm that the use of chymosin preparation derived by fermentation from genetically modified Aspergillus niger van Tieghem variety awamori (Nakazawa) Al-Musallam (A. niger var. awamori) is generally recognized as safe (GRAS)
• 21 CFR* affected: 184.1685 Rennet (animal-derived) and chymosin preparation (fermentation-derived)
• Substance(s)*, (CAS Registry® No.): chymosin preparation, Aspergillus awamori
• Federal Register publication history: Oct 4, 1989 54 FR 40910 Notice ; May 7, 1993 58 FR 27197 Final Rule May 7, 1993

 

*Definitions

• 21 CFR: Title 21 of the Code of Federal Regulations.
• Substance: The name of the substance listed in the CFR.
• CAS Registry® No.: Chemical Abstract Service (CAS) Registry Number® for the substance.
• Petitions (see also Questions and Answers About the Petition Process)
  • FAP: Food Additive Petition
  • CAP: Color Additive Petition
  • GRP: GRAS Affirmation Petition (replaced by GRAS Notification Program in 1998)